The immune system has several checkpoint receptors which dampen the immune response. Checkpoint blockade is a strategy used to relieve this inhibition by blocking these receptors and allowing for more effective antitumor treatment. This project aims to explore the mechanisms by which checkpoint blockade leads to more productive immune responses.
|K. Dane Wittrup, Ph.D.
C. P. Dubbs Professor of Chemical Engineering and Bioengineering
Associate Director, Koch Institute for Integrative Cancer Research
Massachusetts Institute of Technology
500 Main Street,
Cambridge, MA 02139
Office Phone: 617-253-4578
Department of Chemical Engineering
Department of Biological Engineering
Koch Institute for Integrative Cancer Research